Anti-Aging Health Supplements

  In a discovery published in Nature, a team of scientists from Duke-NUS Medical School in Singapore may have found a key to slow aging. The team demonstrated in preclinical models that the protein interleukin-11 (IL-11) actively promotes aging and that removing the IL-11 gene or using an anti-IL-11 antibody dramatically increases the lifespan and health of aging mice. These findings suggest that anti-IL-11 treatments could combat age-related diseases with minimal side effects, offering a promising avenue for future human trials. IL-11 leads to fat accumulation and muscle mass loss, two key hallmarks of aging. This protein has also been linked to several other aging-related problems. It was inherited from fish species approximately 450 million years ago. Chronic inflammation, tissue scarring, metabolic diseases, loss of muscular mass, and cardiac issues are all linked to IL-11.   In preclinical studies, the team found that with age, organs expressed increasing levels ...

Here are some prescription medicines, which may have some off-label use which could benefit aging males. 1. Trimetazidine : Trimetazidine is usually prescribed as a long-term treatment of angina pectoris, and in some countries, for tinnitus and dizziness. It is an anti-ischemic (antianginal) metabolic agent of the fatty acid oxidation inhibitor class, meaning that it improves the heart muscle's ability to use glucose as a fuel by inhibiting its use of fatty acid metabolism. Interestingly, the beneficial actions of trimetazidine in heart failure have not only been observed in patients with an ischemic etiology, but also non-ischemic causes, including idiopathic dilated cardiomyopathy, diabetic cardiomyopathy, and anthracycline-induced cardiotoxicity. Studies have shown that trimetazidine improves Left Ventricular Ejection Fraction (LVEF) and Global Longitudinal Strain in patients with ischemic heart disease and reduced Ejection Fraction. 2. Clomiphene : Clomiphene (or clomiphene cit...

  What is Calcium dobesilate? Calcium, we all know, is essential for strong bones. But calcium dobesilate, a calcium salt of dobesilic acid , is a different thing altogether. This medication acts like a traffic coordinator for your blood cells, particularly in the veins. By improving their flexibility and reducing clumping, calcium dobesilate helps blood flow smoothly, preventing unwanted traffic jams.   Classified as a vasoprotective agent, it has gained recognition for its potential to improve blood vessel health. Calcium Dobesilate is a medication used to treat hemorrhoids (piles) and varicose veins. Calcium Dobesilate works by reducing capillary leakage, thickening blood, and enhancing fluid removal through the lymphatic system.   Calcium Dobesilate Health Benefits: Calcium dobesilate is commonly prescribed to treat conditions related to weak or damaged blood vessels, including: Diabetic retinopathy Diabetic retinopathy, a microvascular complication of diabete...

Antidiabetic agents refer to all the different types of medicine involved in the treatment of diabetes. All these agents aim to reduce blood sugar levels to an acceptable range (called achieving normoglycemia) and relieve symptoms of diabetes such as thirst, excessive urination, and ketoacidosis (a serious complication of diabetes that occurs when the body cannot use glucose as a fuel source). Antidiabetic agents also prevent the development of, or slow the progression of, long-term complications of the disease, such as nephropathy (kidney disease), neuropathy (nerve damage), and retinopathy (damage to the retina of the eye).  Common antidiabetic agents include: ·         - A lpha-glucosidase inhibitors (acarbose, miglitol) ·          -A mylin analogs (pramlintide, cagrilintide) ·         - D ipeptidyl peptidase 4 inhibitors (alogliptan, linagliptan, saxagliptin, sitagliptin) ·         ...

Health Benefits of Arginine L-arginine is an amino acid that helps the body build protein. Your body usually makes all the L-arginine it needs. L-arginine is also found in most protein-rich foods, including fish, red meat, poultry, soy, whole grains, beans and dairy products. As a supplement, L-arginine can be used orally and topically. Arginine is classified as a semi-essential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. Arginine plays an important role in cell division, wound healing, removing ammonia from the body, immune function, and the release of hormones. It is a precursor for the synthesis of nitric oxide (NO), making it important in the regulation of blood pressure. Arginine is necessary for T-cells to function in the body, and can lead to their deregulation if depleted. Arginine is the immediate precursor of nitric oxide, an important signaling molecule which can act as a second messenger, as well as an int...

Beta-alanine is a non-essential amino acid. Most amino acids are building blocks of proteins, but beta-alanine is used to make other chemicals in the body such as carnosine. Beta-alanine binds histidine in the muscles and the brain. The binding creates carnosine. Carnosine is a potent intracellular buffer that stops hydrogen from accumulating. During exercise, hydrogen levels increase, which leads to a burning sensation in your muscles. When that burning becomes too uncomfortable, you stop working out, whether you were truly finished or not. Using supplements of beta-alanine aids in enhancing carnosine levels by 80%. The increase in carnosine levels can prevent lactic acid from building up and causing muscle fatigue during physical exertion. People use beta-alanine for athleticperformance and improving physical performance in elderly adults. It is also used for symptoms of menopause, age-related muscle loss (sarcopenia), and many other conditions.   Improves Exercise Endur...

Carnitine, a non-essential or conditionally-essential amino acid, is the generic term for several compounds, including L-carnitine, acetyl-L-carnitine, and propionyl-L-carnitine. Carnitine is naturally present in many foods—especially foods of animal origin—and is available as a dietary supplement. Carnitine is also synthesized endogenously in the liver, kidneys, and brain from the amino acids, lysine and methionine. Carnitine helps the body break down fatty acids and turn them into energy to power the cells Food Sources of Carnitine Carnitine is present in animal products, especially red meat. Poultry, fish, and dairy foods also provide some carnitine, but vegetables, fruits, and grains provide negligible amounts. Health Benefits of L-Carnitine: Alzheimer’s disease and dementia Carnitine might be conditionally essential in individuals with Alzheimer’s disease because it may support acetylcholine synthesis and help remove toxic compounds to alleviate mitochondrial dysfunction associate...